A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab

A 42-year-old male presented to us after an episode of acute anterior human leukocyte antigen (HLA)-B27-associated uveitis, and intraocular pressure (IOP) in the right eye was 4 mmHg. Ultrasound biomicroscopy revealed ciliary body edema with supraciliary effusion. He was on a frequent topical cortic...

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Autores principales: Majumder, Parthopratim Dutta, Lakra, Ruchika, Yamuna, G, Majumder, Anindya Kishore, Kaushik, Viswanath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032752/
https://www.ncbi.nlm.nih.gov/pubmed/29941755
http://dx.doi.org/10.4103/ijo.IJO_120_18
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author Majumder, Parthopratim Dutta
Lakra, Ruchika
Yamuna, G
Majumder, Anindya Kishore
Kaushik, Viswanath
author_facet Majumder, Parthopratim Dutta
Lakra, Ruchika
Yamuna, G
Majumder, Anindya Kishore
Kaushik, Viswanath
author_sort Majumder, Parthopratim Dutta
collection PubMed
description A 42-year-old male presented to us after an episode of acute anterior human leukocyte antigen (HLA)-B27-associated uveitis, and intraocular pressure (IOP) in the right eye was 4 mmHg. Ultrasound biomicroscopy revealed ciliary body edema with supraciliary effusion. He was on a frequent topical corticosteroid, and oral steroid in addition to receiving a periocular injection depot corticosteroid 20 days back. He was started on treatment with subcutaneous golimumab (GLM). After a month, his IOP in the right eye was 14 mm of Hg with UBM showing resolution of ciliary body edema. GLM can be useful in the management of steroid-resistant cases of HLA B-27-associated ocular hypotony.
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spelling pubmed-60327522018-07-20 A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab Majumder, Parthopratim Dutta Lakra, Ruchika Yamuna, G Majumder, Anindya Kishore Kaushik, Viswanath Indian J Ophthalmol Case Reports A 42-year-old male presented to us after an episode of acute anterior human leukocyte antigen (HLA)-B27-associated uveitis, and intraocular pressure (IOP) in the right eye was 4 mmHg. Ultrasound biomicroscopy revealed ciliary body edema with supraciliary effusion. He was on a frequent topical corticosteroid, and oral steroid in addition to receiving a periocular injection depot corticosteroid 20 days back. He was started on treatment with subcutaneous golimumab (GLM). After a month, his IOP in the right eye was 14 mm of Hg with UBM showing resolution of ciliary body edema. GLM can be useful in the management of steroid-resistant cases of HLA B-27-associated ocular hypotony. Medknow Publications & Media Pvt Ltd 2018-07 /pmc/articles/PMC6032752/ /pubmed/29941755 http://dx.doi.org/10.4103/ijo.IJO_120_18 Text en Copyright: © 2018 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Majumder, Parthopratim Dutta
Lakra, Ruchika
Yamuna, G
Majumder, Anindya Kishore
Kaushik, Viswanath
A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab
title A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab
title_full A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab
title_fullStr A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab
title_full_unstemmed A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab
title_short A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab
title_sort case of human leukocyte antigen b-27-associated ocular hypotony successfully treated with golimumab
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032752/
https://www.ncbi.nlm.nih.gov/pubmed/29941755
http://dx.doi.org/10.4103/ijo.IJO_120_18
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