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Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice
BACKGROUND: Diabetes is a proinflammatory state. Fibrosis of the renal glomerulus is the most common cause of end-stage renal disease. Glomerulosclerosis is caused by the accumulation of extracellular matrix (ECM) proteins in the mesangial interstitial space. Mesangial cells are unique stromal cells...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032782/ https://www.ncbi.nlm.nih.gov/pubmed/29973247 http://dx.doi.org/10.1186/s13287-018-0915-0 |