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DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator

Prostaglandin (PG) D(2) is the ligand for the G‐protein coupled receptors DP1 (D‐type prostanoid receptor 1) and DP2 (also known as chemoattractant receptor homologous molecule, expressed on Th2 cells; CRTH2). Both, DP1 and DP2 are expressed on the cellular surface of eosinophils; although it has be...

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Detalles Bibliográficos
Autores principales: Peinhaupt, Miriam, Roula, David, Theiler, Anna, Sedej, Miriam, Schicho, Rudolf, Marsche, Gunther, Sturm, Eva M., Sabroe, Ian, Rothenberg, Marc E., Heinemann, Akos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032830/
https://www.ncbi.nlm.nih.gov/pubmed/29607536
http://dx.doi.org/10.1002/JLB.3MA1017-404R

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