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DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator
Prostaglandin (PG) D(2) is the ligand for the G‐protein coupled receptors DP1 (D‐type prostanoid receptor 1) and DP2 (also known as chemoattractant receptor homologous molecule, expressed on Th2 cells; CRTH2). Both, DP1 and DP2 are expressed on the cellular surface of eosinophils; although it has be...
Autores principales: | Peinhaupt, Miriam, Roula, David, Theiler, Anna, Sedej, Miriam, Schicho, Rudolf, Marsche, Gunther, Sturm, Eva M., Sabroe, Ian, Rothenberg, Marc E., Heinemann, Akos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032830/ https://www.ncbi.nlm.nih.gov/pubmed/29607536 http://dx.doi.org/10.1002/JLB.3MA1017-404R |
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