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Effects of bed compression on protein separation on gel filtration chromatography at bench and pilot scale
BACKGROUND: Poorly packed chromatography columns are known to reduce drastically the column efficiency and produce broader peaks. Controlled bed compression has been suggested to be a useful approach for solving this problem. Here the relationship between column efficiency and resolution of protein...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032880/ https://www.ncbi.nlm.nih.gov/pubmed/30008505 http://dx.doi.org/10.1002/jctb.5411 |