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Effects of bed compression on protein separation on gel filtration chromatography at bench and pilot scale

BACKGROUND: Poorly packed chromatography columns are known to reduce drastically the column efficiency and produce broader peaks. Controlled bed compression has been suggested to be a useful approach for solving this problem. Here the relationship between column efficiency and resolution of protein...

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Detalles Bibliográficos
Autores principales: Kong, Darryl YC, Gerontas, Spyridon, McCluckie, Ross A, Mewies, Martin, Gruber, David, Titchener‐Hooker, Nigel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032880/
https://www.ncbi.nlm.nih.gov/pubmed/30008505
http://dx.doi.org/10.1002/jctb.5411

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