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A Case of Allergic Urticaria After Ophthalmic Nepafenac Use

A 21-year-old male patient with no history of systemic disease or drug use presented to our clinic with redness and pain in the right eye. Best corrected visual acuity was 20/20 in both eyes. Inflamed pinguecula was observed on slit-lamp examination and the patient was prescribed ophthalmic nepafena...

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Detalles Bibliográficos
Autores principales: Yaşar, Erdoğan, Öztürk Kara, Deniz, Yıldırım, Nilgün
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032958/
https://www.ncbi.nlm.nih.gov/pubmed/29988879
http://dx.doi.org/10.4274/tjo.78614
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author Yaşar, Erdoğan
Öztürk Kara, Deniz
Yıldırım, Nilgün
author_facet Yaşar, Erdoğan
Öztürk Kara, Deniz
Yıldırım, Nilgün
author_sort Yaşar, Erdoğan
collection PubMed
description A 21-year-old male patient with no history of systemic disease or drug use presented to our clinic with redness and pain in the right eye. Best corrected visual acuity was 20/20 in both eyes. Inflamed pinguecula was observed on slit-lamp examination and the patient was prescribed ophthalmic nepafenac eye drops. After instilling the drops that day and the next day, the patient presented again due to pruritus and rash. Upon consultation with the dermatology department, the patient was diagnosed with drug-induced allergic urticaria and the nepafenac drops were discontinued. Although urticaria has been reported as a side effect after systemic non-steroidal anti-inflammatory drug (NSAID) use, such a reaction has not been reported with an ophthalmic NSAID and ours is the first reported case of urticaria following ophthalmic nepafenac use. This unique case highlights the fact that ophthalmologists must also keep urticaria in mind as a potential side effect when prescribing this drug.
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spelling pubmed-60329582018-07-09 A Case of Allergic Urticaria After Ophthalmic Nepafenac Use Yaşar, Erdoğan Öztürk Kara, Deniz Yıldırım, Nilgün Turk J Ophthalmol Case Report A 21-year-old male patient with no history of systemic disease or drug use presented to our clinic with redness and pain in the right eye. Best corrected visual acuity was 20/20 in both eyes. Inflamed pinguecula was observed on slit-lamp examination and the patient was prescribed ophthalmic nepafenac eye drops. After instilling the drops that day and the next day, the patient presented again due to pruritus and rash. Upon consultation with the dermatology department, the patient was diagnosed with drug-induced allergic urticaria and the nepafenac drops were discontinued. Although urticaria has been reported as a side effect after systemic non-steroidal anti-inflammatory drug (NSAID) use, such a reaction has not been reported with an ophthalmic NSAID and ours is the first reported case of urticaria following ophthalmic nepafenac use. This unique case highlights the fact that ophthalmologists must also keep urticaria in mind as a potential side effect when prescribing this drug. Galenos Publishing 2018-06 2018-06-28 /pmc/articles/PMC6032958/ /pubmed/29988879 http://dx.doi.org/10.4274/tjo.78614 Text en ©Turkish Journal of Ophthalmology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yaşar, Erdoğan
Öztürk Kara, Deniz
Yıldırım, Nilgün
A Case of Allergic Urticaria After Ophthalmic Nepafenac Use
title A Case of Allergic Urticaria After Ophthalmic Nepafenac Use
title_full A Case of Allergic Urticaria After Ophthalmic Nepafenac Use
title_fullStr A Case of Allergic Urticaria After Ophthalmic Nepafenac Use
title_full_unstemmed A Case of Allergic Urticaria After Ophthalmic Nepafenac Use
title_short A Case of Allergic Urticaria After Ophthalmic Nepafenac Use
title_sort case of allergic urticaria after ophthalmic nepafenac use
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032958/
https://www.ncbi.nlm.nih.gov/pubmed/29988879
http://dx.doi.org/10.4274/tjo.78614
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