Raman Microspectroscopic Evidence for the Metabolism of a Tyrosine Kinase Inhibitor, Neratinib, in Cancer Cells

Tyrosine kinase receptors are one of the main targets in cancer therapy. They play an essential role in the modulation of growth factor signaling and thereby inducing cell proliferation and growth. Tyrosine kinase inhibitors such as neratinib bind to EGFR and HER2 receptors and exhibit antitumor act...

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Detalles Bibliográficos
Autores principales: Aljakouch, Karim, Lechtonen, Tatjana, Yosef, Hesham K., Hammoud, Mohamad K., Alsaidi, Wissam, Kötting, Carsten, Mügge, Carolin, Kourist, Robert, El‐Mashtoly, Samir F., Gerwert, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033014/
https://www.ncbi.nlm.nih.gov/pubmed/29645336
http://dx.doi.org/10.1002/anie.201803394

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