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Regulation of cellular senescence via the FOXO4‐p53 axis

Forkhead box O (FOXO) and p53 proteins are transcription factors that regulate diverse signalling pathways to control cell cycle, apoptosis and metabolism. In the last decade both FOXO and p53 have been identified as key players in aging, and their misregulation is linked to numerous diseases includ...

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Detalles Bibliográficos
Autores principales: Bourgeois, Benjamin, Madl, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033032/
https://www.ncbi.nlm.nih.gov/pubmed/29683489
http://dx.doi.org/10.1002/1873-3468.13057