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Everolimus dosing recommendations for tuberous sclerosis complex–associated refractory seizures

OBJECTIVE: The present analysis examined the exposure‐response relationship by means of the predose everolimus concentration (C (min)) and the seizure response in patients with tuberous sclerosis complex–associated seizures in the EXIST‐3 study. Recommendations have been made for the target C (min)...

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Detalles Bibliográficos
Autores principales: Franz, David N., Lawson, John A., Yapici, Zuhal, Brandt, Christian, Kohrman, Michael H., Wong, Michael, Milh, Mathieu, Wiemer‐Kruel, Adelheid, Voi, Maurizio, Coello, Neva, Cheung, Wing, Grosch, Kai, French, Jacqueline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033043/
https://www.ncbi.nlm.nih.gov/pubmed/29727013
http://dx.doi.org/10.1111/epi.14085