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Osteoclast-derived SLIT3 is a coupling factor linking bone resorption to bone formation
We identified osteoclast-derived SLIT3 as a new coupling factor using fractionated secretomics. Coupling links bone resorption to bone formation. SLIT3 stimulated the recruitment and proliferation of osteoblasts into bone remodeling sites via activation of β-catenin. Autocrine signaling by SLIT3 als...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korean Society for Biochemistry and Molecular Biology
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033072/ https://www.ncbi.nlm.nih.gov/pubmed/29764562 http://dx.doi.org/10.5483/BMBRep.2018.51.6.109 |