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Analgesic effect of S (+)‐flurbiprofen plaster in a rat model of knee arthritis: analysis of gait and synovial fluid prostaglandin E(2) levels

OBJECTIVES: We developed S (+)‐flurbiprofen plaster (SFPP), a novel NSAID patch containing S (+)‐flurbiprofen (SFP), a potent cyclooxygenase (COX) inhibitor. The purpose of this study was to assess efficacy of SFPP by analysing its effect on the gait disturbance and measuring the prostaglandin E(2)...

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Detalles Bibliográficos
Autores principales: Fukumoto, Ayaka, Tajima, Kyoko, Hori, Miyuki, Toda, Yoshihisa, Kaku, Shinsuke, Matsumoto, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033094/
https://www.ncbi.nlm.nih.gov/pubmed/29607510
http://dx.doi.org/10.1111/jphp.12914

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