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Dobutamine stress-induced ischemic right ventricular dysfunction in patients with three-vessel coronary artery disease

BACKGROUND: Dobutamine stress echocardiography (DSE) is a non-invasive technique to detect coronary artery diseases (CAD). There are limited studies on evaluation of the right ventricular function by stress echocardiography. The appropriate evaluation of RV function and early diagnosis of its failur...

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Autores principales: Bagheri, Ramin Khameneh, Ahmadi, Mostafa, Alimi, Hedyeh, Valaee, Laya, Sahranavard, Toktam, Andalibi, Mohammad Sobhan Sheikh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Electronic physician 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033131/
https://www.ncbi.nlm.nih.gov/pubmed/29997761
http://dx.doi.org/10.19082/6775
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author Bagheri, Ramin Khameneh
Ahmadi, Mostafa
Alimi, Hedyeh
Valaee, Laya
Sahranavard, Toktam
Andalibi, Mohammad Sobhan Sheikh
author_facet Bagheri, Ramin Khameneh
Ahmadi, Mostafa
Alimi, Hedyeh
Valaee, Laya
Sahranavard, Toktam
Andalibi, Mohammad Sobhan Sheikh
author_sort Bagheri, Ramin Khameneh
collection PubMed
description BACKGROUND: Dobutamine stress echocardiography (DSE) is a non-invasive technique to detect coronary artery diseases (CAD). There are limited studies on evaluation of the right ventricular function by stress echocardiography. The appropriate evaluation of RV function and early diagnosis of its failure can help to improve outcomes for the patients undergoing cardiac surgery. OBJECTIVE: To determine right ventricular dysfunction in patients with three-vessel CAD by using DSE. METHODS: This cross-sectional study was among 13 patients who were candidates for coronary artery bypass grafting (CABG) referred to Ghaem Hospital, Mashhad, Iran; from September 2015 to May 2016. After a physical examination and initial measures, DSE was performed and echocardiographic parameters were recorded by a cardiologist. Paired-samples t-test was performed using SPSS Software v.16.0 for data analysis. RESULTS: The study included 13 patients (9 males) with a mean age of 65.4±7.6 years. The mean of TAPS was 16.9±4.5 mm and 15.7±2.9 mm before and after stress echocardiography, respectively (p=0.69). Systolic right ventricular (SRV) peak increased from before DSE compared with after DSE (8.0±2.2 vs. 13.7±4.2 mm/s, p<0.001). In addition, after dobutamine injection, right ventricular (RV) cardiac output decreased in 7 patients and one patient was affected by post-ejection shortening. CONCLUSION: It seems that TAPS and RV cardiac output after injection of dobutamine, can be used as markers for the recognition of ischemic RV dysfunction.
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spelling pubmed-60331312018-07-11 Dobutamine stress-induced ischemic right ventricular dysfunction in patients with three-vessel coronary artery disease Bagheri, Ramin Khameneh Ahmadi, Mostafa Alimi, Hedyeh Valaee, Laya Sahranavard, Toktam Andalibi, Mohammad Sobhan Sheikh Electron Physician Original Article BACKGROUND: Dobutamine stress echocardiography (DSE) is a non-invasive technique to detect coronary artery diseases (CAD). There are limited studies on evaluation of the right ventricular function by stress echocardiography. The appropriate evaluation of RV function and early diagnosis of its failure can help to improve outcomes for the patients undergoing cardiac surgery. OBJECTIVE: To determine right ventricular dysfunction in patients with three-vessel CAD by using DSE. METHODS: This cross-sectional study was among 13 patients who were candidates for coronary artery bypass grafting (CABG) referred to Ghaem Hospital, Mashhad, Iran; from September 2015 to May 2016. After a physical examination and initial measures, DSE was performed and echocardiographic parameters were recorded by a cardiologist. Paired-samples t-test was performed using SPSS Software v.16.0 for data analysis. RESULTS: The study included 13 patients (9 males) with a mean age of 65.4±7.6 years. The mean of TAPS was 16.9±4.5 mm and 15.7±2.9 mm before and after stress echocardiography, respectively (p=0.69). Systolic right ventricular (SRV) peak increased from before DSE compared with after DSE (8.0±2.2 vs. 13.7±4.2 mm/s, p<0.001). In addition, after dobutamine injection, right ventricular (RV) cardiac output decreased in 7 patients and one patient was affected by post-ejection shortening. CONCLUSION: It seems that TAPS and RV cardiac output after injection of dobutamine, can be used as markers for the recognition of ischemic RV dysfunction. Electronic physician 2018-05-05 /pmc/articles/PMC6033131/ /pubmed/29997761 http://dx.doi.org/10.19082/6775 Text en © 2018 The Authors This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (http://creativecommons.org/licenses/by-nc-nd/3.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Original Article
Bagheri, Ramin Khameneh
Ahmadi, Mostafa
Alimi, Hedyeh
Valaee, Laya
Sahranavard, Toktam
Andalibi, Mohammad Sobhan Sheikh
Dobutamine stress-induced ischemic right ventricular dysfunction in patients with three-vessel coronary artery disease
title Dobutamine stress-induced ischemic right ventricular dysfunction in patients with three-vessel coronary artery disease
title_full Dobutamine stress-induced ischemic right ventricular dysfunction in patients with three-vessel coronary artery disease
title_fullStr Dobutamine stress-induced ischemic right ventricular dysfunction in patients with three-vessel coronary artery disease
title_full_unstemmed Dobutamine stress-induced ischemic right ventricular dysfunction in patients with three-vessel coronary artery disease
title_short Dobutamine stress-induced ischemic right ventricular dysfunction in patients with three-vessel coronary artery disease
title_sort dobutamine stress-induced ischemic right ventricular dysfunction in patients with three-vessel coronary artery disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033131/
https://www.ncbi.nlm.nih.gov/pubmed/29997761
http://dx.doi.org/10.19082/6775
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