Predicting the spectrum of TCR repertoire sharing with a data‐driven model of recombination

Despite the extreme diversity of T‐cell repertoires, many identical T‐cell receptor (TCR) sequences are found in a large number of individual mice and humans. These widely shared sequences, often referred to as “public,” have been suggested to be over‐represented due to their potential immune functi...

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Detalles Bibliográficos
Autores principales: Elhanati, Yuval, Sethna, Zachary, Callan, Curtis G., Mora, Thierry, Walczak, Aleksandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Invited Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033145/
https://www.ncbi.nlm.nih.gov/pubmed/29944757
http://dx.doi.org/10.1111/imr.12665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033145/
https://www.ncbi.nlm.nih.gov/pubmed/29944757
http://dx.doi.org/10.1111/imr.12665

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