Cargando…
Predicting the spectrum of TCR repertoire sharing with a data‐driven model of recombination
Despite the extreme diversity of T‐cell repertoires, many identical T‐cell receptor (TCR) sequences are found in a large number of individual mice and humans. These widely shared sequences, often referred to as “public,” have been suggested to be over‐represented due to their potential immune functi...
Autores principales: | Elhanati, Yuval, Sethna, Zachary, Callan, Curtis G., Mora, Thierry, Walczak, Aleksandra M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033145/ https://www.ncbi.nlm.nih.gov/pubmed/29944757 http://dx.doi.org/10.1111/imr.12665 |
Ejemplares similares
-
Inferring processes underlying B-cell repertoire diversity
por: Elhanati, Yuval, et al.
Publicado: (2015) -
Population variability in the generation and selection of T-cell repertoires
por: Sethna, Zachary, et al.
Publicado: (2020) -
OLGA: fast computation of generation probabilities of B- and T-cell receptor amino acid sequences and motifs
por: Sethna, Zachary, et al.
Publicado: (2019) -
Genetic and environmental determinants of human TCR repertoire diversity
por: Krishna, Chirag, et al.
Publicado: (2020) -
Evidence for Shaping of Light Chain Repertoire by Structural Selection
por: Toledano, Adar, et al.
Publicado: (2018)