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Inhibition of CRM1 activity sensitizes endometrial and ovarian cell lines to TRAIL-induced cell death
BACKGROUND: CRM1 enrichment has been shown to be indicative of invasive as well as chemoresistant tumors. On the other hand, TRAIL, a powerful and specific anti-tumoral agent, has yet to be used effectively to treat gynecological tumors in patients. In the present study, we examined if CRM1, a nucle...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033231/ https://www.ncbi.nlm.nih.gov/pubmed/29973205 http://dx.doi.org/10.1186/s12964-018-0252-z |