Cargando…

Class III β-Tubulin Overexpression Induces Chemoresistance to Eribulin in a Leiomyosarcoma Cell Line

Eribulin is a new drug to treat soft tissue sarcoma (STS) that exerts antitumor activity by binding to microtubules. The prognosis of STS is poor, and eribulin is expected to improve the treatment outcome. We observed several cases that exhibited resistance to eribulin and developed an eribulin-resi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yahiro, Kenichiro, Matsumoto, Yoshihiro, Fukushi, Jun-ichi, Kawaguchi, Ken-ichi, Endo, Makoto, Setsu, Nokitaka, IIda, Keiichiro, Fukushima, Suguru, Nakagawa, Makoto, Kimura, Atsushi, Oda, Yoshinao, Nakashima, Yasuharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033248/ https://www.ncbi.nlm.nih.gov/pubmed/30034996 http://dx.doi.org/10.1155/2018/8987568

Ejemplares similares

Correction: Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor
por: Fukushima, Suguru, et al.
Publicado: (2018)

Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor
por: Fukushima, Suguru, et al.
Publicado: (2017)

Clinical Outcome and Prognostic Factors of Malignant Spinal Dumbbell Tumors
por: Matsumoto, Yoshihiro, et al.
Publicado: (2018)

Evaluation of Risk Factors for Vertebral Compression Fracture after Carbon-Ion Radiotherapy for Primary Spinal and Paraspinal Sarcoma
por: Matsumoto, Yoshihiro, et al.
Publicado: (2017)

Nuclear β-catenin translocation plays a key role in osteoblast differentiation of giant cell tumor of bone
por: Kimura, Atsushi, et al.
Publicado: (2022)

Metabolic Tumor Volume by (18)F-FDG PET/CT Can Predict the Clinical Outcome of Primary Malignant Spine/Spinal Tumors
por: Matsumoto, Yoshihiro, et al.
Publicado: (2017)

Risk Factors of Periprosthetic Infection in Patients with Tumor Prostheses Following Resection for Musculoskeletal Tumor of the Lower Limb
por: Fujiwara, Toshifumi, et al.
Publicado: (2020)

Postoperative clinical and functional outcomes in patients with tumor and tumor-like lesion of foot and ankle
por: Kokubu, Yasuhiko, et al.
Publicado: (2022)

Shape Factor of the Spinal Cord: A Possible Predictor of Surgical Outcome for Intradural Extramedullary Spinal Tumors in the Thoracic Spine
por: Matsumoto, Yoshihiro, et al.
Publicado: (2021)

Older age at surgery and postoperative leg length discrepancy are risk factors for unfavourable patient-reported outcome measures of knee tumour endoprostheses following resection for musculoskeletal tumour of the lower limb
por: Kokubu, Yasuhiko, et al.
Publicado: (2023)

Does the Use of Peripheral Immune-Related Markers Indicate Whether to Administer Pazopanib, Trabectedin, or Eribulin to Advanced Soft Tissue Sarcoma Patients?
por: Shimada, Eijiro, et al.
Publicado: (2021)

The neurological outcome of radiotherapy versus surgery in patients with metastatic spinal cord compression presenting with myelopathy
por: Iida, Keiichiro, et al.
Publicado: (2017)

Clinical, Radiological, and Histopathological Characteristics of Periosteal Chondrosarcoma with a Focus on the Frequency of Medullary Invasion
por: Nakagawa, Makoto, et al.
Publicado: (2022)

Eribulin as a first-line treatment for soft tissue sarcoma patients with contraindications for doxorubicin
por: Tsuchihashi, Kenji, et al.
Publicado: (2020)

miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor
por: Iida, Keiichiro, et al.
Publicado: (2013)

Expression of Forkhead box M1 in soft tissue leiomyosarcoma: Clinicopathologic and in vitro study using a newly established cell line
por: Maekawa, Akira, et al.
Publicado: (2016)

Preclinical activity of selinexor in combination with eribulin in uterine leiomyosarcoma
por: Mittal, Sonam, et al.
Publicado: (2023)

Eribulin in Patients with Liposarcoma and Leiomyosarcoma: A Retrospective Single-Center Experience
por: Steinbrecher, Oskar, et al.
Publicado: (2023)

Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition
por: Oba, Takaaki, et al.
Publicado: (2018)

Activation of ERK1/2 Causes Pazopanib Resistance via Downregulation of DUSP6 in Synovial Sarcoma Cells
por: Yokoyama, Nobuhiko, et al.
Publicado: (2017)

Effect of cartilaginous endplates on extruded disc resorption in lumbar disc herniation
por: Kawaguchi, Kenichi, et al.
Publicado: (2018)

Malignant transformation of phosphaturic mesenchymal tumor: a case report and literature review
por: Oyama, Noriko, et al.
Publicado: (2020)

Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma
por: Sampson, Valerie B., et al.
Publicado: (2016)

Therapeutic efficacy of a four-year treatment with eribulin in a patient with uterine leiomyosarcoma: A case report
por: Matsuura, Motoki, et al.
Publicado: (2023)

Eribulin versus dacarbazine in patients with leiomyosarcoma: subgroup analysis from a phase 3, open-label, randomised study
por: Blay, Jean-Yves, et al.
Publicado: (2019)

ABCB1 and ABCC11 confer resistance to eribulin in breast cancer cell lines
por: Oba, Takaaki, et al.
Publicado: (2016)

Anatomic Reconstruction of Lateral Ankle Ligaments and Both Peroneus Tendons After Open Fracture Dislocation of the Ankle: A Case Report
por: Sakurai, Ryuta, et al.
Publicado: (2019)

Interim results of a real-world observational study of eribulin in soft tissue sarcoma including rare subtypes
por: Kobayashi, Eisuke, et al.
Publicado: (2019)

Influence of dioxin-related compounds on physical function in Yusho incident victims
por: Fukushi, Jun-ichi, et al.
Publicado: (2019)

Simultaneous reconstruction of the bone and vessels for complex femoral defect
por: Miyamoto, Shimpei, et al.
Publicado: (2016)

Eribulin drug review
por: Shetty, Nishitha, et al.
Publicado: (2014)

Eribulin in Cancer Treatment
por: Swami, Umang, et al.
Publicado: (2015)

The Expression of Insulin-Like Growth Factor II Messenger RNA-Binding Protein 3 Upregulated in Intradural Extramedullary Schwannomas
por: Bekki, Hirofumi, et al.
Publicado: (2022)

Prognostic value of nuclear morphometry in myxoid liposarcoma
por: Kawaguchi, Kengo, et al.
Publicado: (2023)

Complete Surgical Resection of a Leiomyosarcoma Arising from the Inferior Vena Cava
por: Sonoda, Hirofumi, et al.
Publicado: (2015)

βIII-Tubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer
por: McCarroll, Joshua A., et al.
Publicado: (2014)

Sustaining self-restraint until the middle of the COVID-19 pandemic in Tokyo
por: Ishii, Yoshinao, et al.
Publicado: (2022)

Fibroma of Tendon Sheath Presenting Limited Flexion of the Fingers
por: Maeda, Kazuhiro, et al.
Publicado: (2017)

Kyphosis Progression after Balloon Kyphoplasty Compared with Conservative Treatment
por: Iida, Keiichiro, et al.
Publicado: (2019)

The Posterolaterally Oriented and Laterally Downward Sloping Facet Joint Is a Risk Factor for Degenerative Cervical Spondylolisthesis and Myelopathy
por: Kumamaru, Hiromi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ui908d903inu1pcbf6orr8gtcb