Weak HIF-1alpha expression indicates poor prognosis in resectable pancreatic ductal adenocarcinoma

BACKGROUND: HIF-1alpha and CAIX proteins are commonly expressed under hypoxic conditions, but other regulatory factors have been described as well. Pancreatic ductal adenocarcinoma (PDAC) is characterized by hypoxia and strong stromal reaction and has a dismal prognosis with the currently available...

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Detalles Bibliográficos
Autores principales: Leppänen, Joni, Helminen, Olli, Huhta, Heikki, Kauppila, Joonas H., Isohookana, Joel, Haapasaari, Kirsi-Maria, Parkkila, Seppo, Saarnio, Juha, Lehenkari, Petri P., Karttunen, Tuomo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033289/
https://www.ncbi.nlm.nih.gov/pubmed/29973215
http://dx.doi.org/10.1186/s12957-018-1432-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033289/
https://www.ncbi.nlm.nih.gov/pubmed/29973215
http://dx.doi.org/10.1186/s12957-018-1432-4

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