How low can we go? The implications of low bacterial load in respiratory microbiota studies

BACKGROUND: Culture-independent sequencing methods are increasingly used to investigate the microbiota associated with human mucosal surfaces, including sites that have low bacterial load in healthy individuals (e.g. the lungs). Standard microbiota methods developed for analysis of high bacterial lo...

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Detalles Bibliográficos
Autores principales: Marsh, Robyn L., Nelson, Maria T., Pope, Chris E., Leach, Amanda J., Hoffman, Lucas R., Chang, Anne B., Smith-Vaughan, Heidi C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033291/
https://www.ncbi.nlm.nih.gov/pubmed/30003009
http://dx.doi.org/10.1186/s41479-018-0051-8

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