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Silencing NIK potentiates anti-VEGF therapy in a novel 3D model of colorectal cancer angiogenesis

Angiogenesis is essential for colorectal cancer (CRC) progression, as demonstrated by the beneficial clinical effects of therapeutics inhibiting VEGF signaling. However, alternative mechanisms of neovascularization can develop, resulting in treatment failure. Previously we demonstrated NF-κB-inducin...

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Detalles Bibliográficos
Autores principales:	Maracle, Chrissta X., Jeucken, Kim C.M., Helder, Boy, van Gulik, Thomas M., Steins, Anne, van Laarhoven, Hanneke W.M., Tas, Sander W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033358/ https://www.ncbi.nlm.nih.gov/pubmed/29983872 http://dx.doi.org/10.18632/oncotarget.25442

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