Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids

Ulcerative colitis (UC) is a prevalent form of inflammatory bowel disease (IBD) whose pathogenic mechanisms remain unclear. Elucidating these mechanisms is important to reduce UC symptoms and to prevent UC progression into colitis-associated colon cancer (CAC). Our goal was to develop and validate f...

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Detalles Bibliográficos
Autores principales: Sarvestani, Samaneh K., Signs, Steven A., Lefebvre, Veronique, Mack, Stephen, Ni, Ying, Morton, Andrew, Chan, Ernest R., Li, Xiaoxia, Fox, Paul, Ting, Angela, Kalady, Matthew F., Cruise, Michael, Ashburn, Jean, Stiene, Jennifer, Lai, Wei, Liska, David, Xiang, Shao, Huang, Emina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033374/
https://www.ncbi.nlm.nih.gov/pubmed/29983891
http://dx.doi.org/10.18632/oncotarget.25617

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