Role of critical elements in botulinum neurotoxin complex in toxin routing across intestinal and bronchial barriers

The highly potent botulinum neurotoxin serotype A (BoNT/A) inhibits neurotransmitter release at neuromuscular junctions resulting in flaccid muscle paralysis, respiratory arrest and death. In order to reach their neuronal cell targets, BoNT/A must cross epithelial cell barriers lining the intestines...

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Detalles Bibliográficos
Autores principales: Ghosal, Koyel J., Patel, Kruti, Singh, Bal Ram, Hale, Martha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033393/
https://www.ncbi.nlm.nih.gov/pubmed/29975725
http://dx.doi.org/10.1371/journal.pone.0199524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033393/
https://www.ncbi.nlm.nih.gov/pubmed/29975725
http://dx.doi.org/10.1371/journal.pone.0199524

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