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Role of critical elements in botulinum neurotoxin complex in toxin routing across intestinal and bronchial barriers
The highly potent botulinum neurotoxin serotype A (BoNT/A) inhibits neurotransmitter release at neuromuscular junctions resulting in flaccid muscle paralysis, respiratory arrest and death. In order to reach their neuronal cell targets, BoNT/A must cross epithelial cell barriers lining the intestines...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033393/ https://www.ncbi.nlm.nih.gov/pubmed/29975725 http://dx.doi.org/10.1371/journal.pone.0199524 |