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Fast score test with global null estimation regardless of missing genotypes
In genome-wide association studies (GWASs) for binary traits (or case-control samples) in the presence of covariates to be adjusted for, researchers often use a logistic regression model to test variants for disease association. Popular tests include Wald, likelihood ratio, and score tests. For like...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033421/ https://www.ncbi.nlm.nih.gov/pubmed/29975732 http://dx.doi.org/10.1371/journal.pone.0199692 |