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Detection of PrP(res) in peripheral tissue in pigs with clinical disease induced by intracerebral challenge with sheep-passaged bovine spongiform encephalopathy agent
Bovine spongiform encephalopathy (BSE) can be efficiently transmitted to pigs via intracerebral inoculation. A clear link has been established between the consumption of products of bovine origin contaminated with the BSE agent and the development of variant Creutzfeldt-Jakob disease in humans. Smal...
Autores principales: | Hedman, Carlos, Otero, Alicia, Douet, Jean-Yves, Lacroux, Caroline, Lugan, Séverine, Filali, Hicham, Corbière, Fabien, Aron, Naima, Badiola, Juan José, Andréoletti, Olivier, Bolea, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033439/ https://www.ncbi.nlm.nih.gov/pubmed/29975760 http://dx.doi.org/10.1371/journal.pone.0199914 |
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