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B cell clonal lineage alterations upon recombinant HIV-1 envelope immunization of rhesus macaques

Broadly neutralizing HIV-1 antibodies (bNAbs) isolated from infected subjects display protective potential in animal models. Their elicitation by immunization is thus highly desirable. The HIV-1 envelope glycoprotein (Env) is the sole viral target of bnAbs, but is also targeted by binding, non-neutr...

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Detalles Bibliográficos
Autores principales: Yacoob, Christina, Lange, Miles Darnell, Cohen, Kristen, Lathia, Kanan, Feng, Junli, Glenn, Jolene, Carbonetti, Sara, Oliver, Brian, Vigdorovich, Vladimir, Sather, David Noah, Stamatatos, Leonidas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033445/
https://www.ncbi.nlm.nih.gov/pubmed/29933399
http://dx.doi.org/10.1371/journal.ppat.1007120