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Alternative splicing of helicase-like transcription factor (Hltf): Intron retention-dependent activation of immune tolerance at the feto-maternal interface

Hltf is regulated by intron retention, and global Hltf-deletion causes perinatal lethality from hypoglycemia. In heart, full-length Hltf is a transcriptional regulator of Hif-1α that controls transport systems. Thus, we tested the hypothesis that Hltf deletion from placenta caused or exacerbated neo...

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Detalles Bibliográficos
Autores principales:	Kaur, Gurvinder, Helmer, Rebecca A., Smith, Lisa A., Martinez-Zaguilan, Raul, Dufour, Jannette M., Chilton, Beverly S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033450/ https://www.ncbi.nlm.nih.gov/pubmed/29975766 http://dx.doi.org/10.1371/journal.pone.0200211

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