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Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans

Misfolding and accumulation of cellular protein aggregates are pathological hallmarks of aging and neurodegeneration. One such protein is α-synuclein, which when misfolded, forms aggregates and disrupts normal cellular functions of the neurons causing Parkinson’s disease. Nutritional interventions a...

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Detalles Bibliográficos
Autores principales:	Maulik, Malabika, Mitra, Swarup, Hunter, Skyler, Hunstiger, Moriah, Oliver, S. Ryan, Bult-Ito, Abel, Taylor, Barbara E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033853/ https://www.ncbi.nlm.nih.gov/pubmed/29976995 http://dx.doi.org/10.1038/s41598-018-26905-4

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