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The frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage

Hydrocephalus is a common complication following subarachnoid haemorrhage (SAH) arising from spontaneous aneurysm rupture. The Hounsfield unit (HU) value from computed tomography scans may reflect bone mineral density, which correlates with body mass index, which in turn is related to post-SAH ventr...

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Autores principales: Won, Yu Deok, Na, Min Kyun, Kim, Choong Hyun, Kim, Jae Min, Cheong, Jin Hwan, Ryu, Je Il, Han, Myung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033863/
https://www.ncbi.nlm.nih.gov/pubmed/29977066
http://dx.doi.org/10.1038/s41598-018-28471-1
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author Won, Yu Deok
Na, Min Kyun
Kim, Choong Hyun
Kim, Jae Min
Cheong, Jin Hwan
Ryu, Je Il
Han, Myung-Hoon
author_facet Won, Yu Deok
Na, Min Kyun
Kim, Choong Hyun
Kim, Jae Min
Cheong, Jin Hwan
Ryu, Je Il
Han, Myung-Hoon
author_sort Won, Yu Deok
collection PubMed
description Hydrocephalus is a common complication following subarachnoid haemorrhage (SAH) arising from spontaneous aneurysm rupture. The Hounsfield unit (HU) value from computed tomography scans may reflect bone mineral density, which correlates with body mass index, which in turn is related to post-SAH ventricle size changes. We herein investigated potential associations between frontal skull HU values and ventricle size changes after SAH. HU values from four different areas in the frontal bone were averaged to minimize measurement errors. The bicaudate index and Evans ratio were measured using both baseline and follow-up CT images. CT images with bicaudate index >0.2 and Evans ratio >0.3 simultaneously were defined as indicating ventriculomegaly. We included 232 consecutive patients with SAH due to primary spontaneous aneurysm rupture, who underwent clipping over almost a 9-year period at a single institution. The first tertile of frontal skull HU values in older patients (≥55 years) was an independent predictor of ventriculomegaly after SAH, as compared to the third tertile in younger patients (hazard ratio, 4.01; 95% confidence interval 1.21–13.30; p = 0.023). The lower frontal skull HU value independently predicted ventricular enlargement post-SAH, due to the potential weak integrity of subarachnoid trabecular structures in younger patients.
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spelling pubmed-60338632018-07-12 The frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage Won, Yu Deok Na, Min Kyun Kim, Choong Hyun Kim, Jae Min Cheong, Jin Hwan Ryu, Je Il Han, Myung-Hoon Sci Rep Article Hydrocephalus is a common complication following subarachnoid haemorrhage (SAH) arising from spontaneous aneurysm rupture. The Hounsfield unit (HU) value from computed tomography scans may reflect bone mineral density, which correlates with body mass index, which in turn is related to post-SAH ventricle size changes. We herein investigated potential associations between frontal skull HU values and ventricle size changes after SAH. HU values from four different areas in the frontal bone were averaged to minimize measurement errors. The bicaudate index and Evans ratio were measured using both baseline and follow-up CT images. CT images with bicaudate index >0.2 and Evans ratio >0.3 simultaneously were defined as indicating ventriculomegaly. We included 232 consecutive patients with SAH due to primary spontaneous aneurysm rupture, who underwent clipping over almost a 9-year period at a single institution. The first tertile of frontal skull HU values in older patients (≥55 years) was an independent predictor of ventriculomegaly after SAH, as compared to the third tertile in younger patients (hazard ratio, 4.01; 95% confidence interval 1.21–13.30; p = 0.023). The lower frontal skull HU value independently predicted ventricular enlargement post-SAH, due to the potential weak integrity of subarachnoid trabecular structures in younger patients. Nature Publishing Group UK 2018-07-05 /pmc/articles/PMC6033863/ /pubmed/29977066 http://dx.doi.org/10.1038/s41598-018-28471-1 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Won, Yu Deok
Na, Min Kyun
Kim, Choong Hyun
Kim, Jae Min
Cheong, Jin Hwan
Ryu, Je Il
Han, Myung-Hoon
The frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage
title The frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage
title_full The frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage
title_fullStr The frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage
title_full_unstemmed The frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage
title_short The frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage
title_sort frontal skull hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033863/
https://www.ncbi.nlm.nih.gov/pubmed/29977066
http://dx.doi.org/10.1038/s41598-018-28471-1
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