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Increased risk for inflammatory bowel disease in congenital hypothyroidism supports the existence of a shared susceptibility factor
Loss-of-function mutations in dual oxidase (DUOX) 2 are the most common genetic variants found in congenital hypothyroidism (CH), and similar mutations have been recently reported in few very-early-onset inflammatory bowel disease (IBD) patients without CH. If DUOX2 variants indeed increase suscepti...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033893/ https://www.ncbi.nlm.nih.gov/pubmed/29977049 http://dx.doi.org/10.1038/s41598-018-28586-5 |