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Feeders facilitate telomere maintenance and chromosomal stability of embryonic stem cells

Feeder cells like mouse embryonic fibroblasts (MEFs) have been widely applied for culture of pluripotent stem cells, but their roles remain elusive. Noticeably, ESCs cultured on the feeders display transcriptional heterogeneity. We investigated roles of feeder cells by examining the telomere mainten...

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Detalles Bibliográficos
Autores principales:	Guo, Renpeng, Ye, Xiaoying, Yang, Jiao, Zhou, Zhongcheng, Tian, Chenglei, Wang, Hua, Wang, Haiying, Fu, Haifeng, Liu, Chun, Zeng, Ming, Yang, Jun, Liu, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033898/ https://www.ncbi.nlm.nih.gov/pubmed/29976922 http://dx.doi.org/10.1038/s41467-018-05038-2

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