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A window of opportunity for cooperativity in the T Cell Receptor

The T-cell antigen receptor (TCR) is pre-organised in oligomers, known as nanoclusters. Nanoclusters could provide a framework for inter-TCR cooperativity upon peptide antigen-major histocompatibility complex (pMHC) binding. Here we have used soluble pMHC oligomers in search for cooperativity effect...

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Detalles Bibliográficos
Autores principales: Martin-Blanco, N., Blanco, R., Alda-Catalinas, C., Bovolenta, E. R., Oeste, C. L., Palmer, E., Schamel, W. W., Lythe, G., Molina-París, C., Castro, M., Alarcon, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033938/
https://www.ncbi.nlm.nih.gov/pubmed/29976994
http://dx.doi.org/10.1038/s41467-018-05050-6

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