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A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics

The highly efficient cancer cell targeted delivery plays an important role in precise targeted therapies. Herein, a multifunctional DNA nano-scorpion nanostructure (termed AptDzy-DNS) functioned with aptamers and DNAzyme is developed for highly efficient targeted delivery of mRNA therapeutics in gen...

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Detalles Bibliográficos
Autores principales: Li, Dandan, Mo, Fei, Wu, Jiangling, Huang, Yong, Zhou, Huihao, Ding, Shijia, Chen, Weixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033943/
https://www.ncbi.nlm.nih.gov/pubmed/29976947
http://dx.doi.org/10.1038/s41598-018-28542-3