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ATR is a multifunctional regulator of male mouse meiosis

Meiotic cells undergo genetic exchange between homologs through programmed DNA double-strand break (DSB) formation, recombination and synapsis. In mice, the DNA damage-regulated phosphatidylinositol-3-kinase-like kinase (PIKK) ATM regulates all of these processes. However, the meiotic functions of t...

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Detalles Bibliográficos
Autores principales:	Widger, Alexander, Mahadevaiah, Shantha K., Lange, Julian, ElInati, Elias, Zohren, Jasmin, Hirota, Takayuki, Pacheco, Sarai, Maldonado-Linares, Andros, Stanzione, Marcello, Ojarikre, Obah, Maciulyte, Valdone, de Rooij, Dirk G., Tóth, Attila, Roig, Ignasi, Keeney, Scott, Turner, James M.A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033951/ https://www.ncbi.nlm.nih.gov/pubmed/29976923 http://dx.doi.org/10.1038/s41467-018-04850-0

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