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Chronic lung disease, lung regeneration and future therapeutic strategies

Chronic lung diseases have been recognized as one of the world's leading causes of death in recent decades. Lacking effective treatments brings the patients not only bad quality of life but also higher risk for lung cancer development. By increasing the understanding of deeper mechanism of how...

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Detalles Bibliográficos
Autores principales: Cao, Xuan-Ye, Xiao, Si-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Medical Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034004/
https://www.ncbi.nlm.nih.gov/pubmed/29988916
http://dx.doi.org/10.1016/j.cdtm.2018.05.001
Descripción
Sumario:Chronic lung diseases have been recognized as one of the world's leading causes of death in recent decades. Lacking effective treatments brings the patients not only bad quality of life but also higher risk for lung cancer development. By increasing the understanding of deeper mechanism of how lung develops and regenerates, researchers now focus on studying lung regenerative medicine, aiming to apply different and more efficient therapies to treat chronic lung diseases. This review will provide a wide picture of both basic lung developmental, regeneration mechanism and different designed strategies for treating chronic lung diseases in the future decades.