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DNA methylation in the pathogenesis of type 2 diabetes in humans

BACKGROUND: Type 2 diabetes (T2D) is a multifactorial, polygenic disease caused by impaired insulin secretion and insulin resistance. Genome-wide association studies (GWAS) were expected to resolve a large part of the genetic component of diabetes; yet, the single nucleotide polymorphisms identified...

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Detalles Bibliográficos
Autores principales:	Davegårdh, Cajsa, García-Calzón, Sonia, Bacos, Karl, Ling, Charlotte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Special Section on Epigenetics (2018)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034041/ https://www.ncbi.nlm.nih.gov/pubmed/29496428 http://dx.doi.org/10.1016/j.molmet.2018.01.022

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