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The 5′ Untranslated Region of the EFG1 Transcript Promotes Its Translation To Regulate Hyphal Morphogenesis in Candida albicans

Extensive 5′ untranslated regions (UTR) are a hallmark of transcripts determining hyphal morphogenesis in Candida albicans. The major transcripts of the EFG1 gene, which are responsible for cellular morphogenesis and metabolism, contain a 5′ UTR of up to 1,170 nucleotides (nt). Deletion analyses of...

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Detalles Bibliográficos
Autores principales: Desai, Prashant R., Lengeler, Klaus, Kapitan, Mario, Janßen, Silas Matthias, Alepuz, Paula, Jacobsen, Ilse D., Ernst, Joachim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034079/
https://www.ncbi.nlm.nih.gov/pubmed/29976646
http://dx.doi.org/10.1128/mSphere.00280-18