Role of MCP-1 and CCR2 in ethanol-induced neuroinflammation and neurodegeneration in the developing brain

BACKGROUND: Neuroinflammation and microglial activation have been implicated in both alcohol use disorders (AUD) and fetal alcohol spectrum disorders (FASD). Chemokine monocyte chemoattractant protein 1 (MCP-1) and its receptor C-C chemokine receptor type 2 (CCR2) are critical mediators of neuroinfl...

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Detalles Bibliográficos
Autores principales: Zhang, Kai, Wang, Haiping, Xu, Mei, Frank, Jacqueline A., Luo, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034273/
https://www.ncbi.nlm.nih.gov/pubmed/29976212
http://dx.doi.org/10.1186/s12974-018-1241-2

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