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Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer
BACKGROUND: The theory of field effect suggests that the tumor-adjacent area, besides histopathologically normal, undergoes genetic and epigenetic changes that can eventually affect epithelial homeostasis, predisposing the patient to cancer development. One of the many molecular changes described in...
Autores principales: | Lopes, Camile B., Magalhães, Leandro L., Teófilo, Carolina R., Alves, Ana Paula N. N., Montenegro, Raquel C., Negrini, Massimo, Ribeiro-dos-Santos, Ândrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034275/ https://www.ncbi.nlm.nih.gov/pubmed/29976158 http://dx.doi.org/10.1186/s12885-018-4631-z |
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