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Evaluation of α-tubulin, detyrosinated α-tubulin, and vimentin in CTCs: identification of the interaction between CTCs and blood cells through cytoskeletal elements

BACKGROUND: Circulating tumor cells (CTCs) are the major players in the metastatic process. A potential mechanism of cell migration and invasion is the formation of microtentacles in tumor cells. These structures are supported by α-tubulin (TUB), detyrosinated α-tubulin (GLU), and vimentin (VIM). In...

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Detalles Bibliográficos
Autores principales: Kallergi, G., Aggouraki, D., Zacharopoulou, N., Stournaras, C., Georgoulias, V., Martin, S. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034292/
https://www.ncbi.nlm.nih.gov/pubmed/29976237
http://dx.doi.org/10.1186/s13058-018-0993-z

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