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Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane
Sulforaphane is a small molecule isothiocyanate which exhibits anticancer potential, yet its biological targets remain poorly understood. Here we employ a competition-based chemical proteomics strategy to profile sulforaphane's targets and identify over 500 targets along with their relative aff...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034444/ https://www.ncbi.nlm.nih.gov/pubmed/28439590 http://dx.doi.org/10.1039/c6cc08797c |