Cargando…
Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane
Sulforaphane is a small molecule isothiocyanate which exhibits anticancer potential, yet its biological targets remain poorly understood. Here we employ a competition-based chemical proteomics strategy to profile sulforaphane's targets and identify over 500 targets along with their relative aff...
Autores principales: | Clulow, James A., Storck, Elisabeth M., Lanyon-Hogg, Thomas, Kalesh, Karunakaran A., Jones, Lyn H., Tate, Edward W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034444/ https://www.ncbi.nlm.nih.gov/pubmed/28439590 http://dx.doi.org/10.1039/c6cc08797c |
Ejemplares similares
-
Global profiling of protein lipidation using chemical proteomic technologies
por: Tate, Edward W, et al.
Publicado: (2015) -
Defeating the trypanosomatid trio: proteomics of the protozoan parasites causing neglected tropical diseases
por: Parthasarathy, Anutthaman, et al.
Publicado: (2020) -
An Integrated Chemical Proteomics Approach for Quantitative Profiling of Intracellular ADP-Ribosylation
por: Kalesh, Karunakaran, et al.
Publicado: (2019) -
Dual Chemical Probes Enable Quantitative System-Wide Analysis of Protein Prenylation and Prenylation Dynamics
por: Storck, Elisabeth M., et al.
Publicado: (2019) -
Quantitative Proteomics Reveals that Hsp90 Inhibition Dynamically Regulates Global Protein Synthesis in Leishmania mexicana
por: Kalesh, Karunakaran, et al.
Publicado: (2021)