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Empagliflozin Prevents Worsening of Cardiac Function in an Experimental Model of Pressure Overload-Induced Heart Failure

This study sought to determine whether the sodium/glucose cotransporter 2 (SGLT2) inhibitor empagliflozin improved heart failure (HF) outcomes in nondiabetic mice. The EMPA-REG OUTCOME (Empagliflozin, Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients) trial demonstrated that em...

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Detalles Bibliográficos
Autores principales:	Byrne, Nikole J., Parajuli, Nirmal, Levasseur, Jody L., Boisvenue, Jamie, Beker, Donna L., Masson, Grant, Fedak, Paul W.M., Verma, Subodh, Dyck, Jason R.B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	LEADING EDGE IN TRANSLATIONAL RESEARCH
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034464/ https://www.ncbi.nlm.nih.gov/pubmed/30062155 http://dx.doi.org/10.1016/j.jacbts.2017.07.003

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