Metastatic clear cell renal cell carcinoma demonstrating intense uptake on (68)Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature

(68)Ga-DOTATATE positron emission tomography (PET) is a molecular imaging technology which has shown superiority over (111)In-octreotide scanning for the detection and staging of neuroendocrine tumors. We report three patients with pancreatic masses that were ultimately diagnosed as clear cell renal...

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Autores principales: Nadebaum, David P., Lee, Sze Ting, Nikfarjam, Mehrdad, Scott, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034548/
https://www.ncbi.nlm.nih.gov/pubmed/30034285
http://dx.doi.org/10.4103/wjnm.WJNM_38_17
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author Nadebaum, David P.
Lee, Sze Ting
Nikfarjam, Mehrdad
Scott, Andrew M.
author_facet Nadebaum, David P.
Lee, Sze Ting
Nikfarjam, Mehrdad
Scott, Andrew M.
author_sort Nadebaum, David P.
collection PubMed
description (68)Ga-DOTATATE positron emission tomography (PET) is a molecular imaging technology which has shown superiority over (111)In-octreotide scanning for the detection and staging of neuroendocrine tumors. We report three patients with pancreatic masses that were ultimately diagnosed as clear cell renal cell carcinoma (ccRCC) metastases on histopathology. During their initial diagnostic assessment, the three patients underwent both (18)F-fluorodeoxyglucose ((18)F-FDG) and (68)Ga-DOTATATE PET. While all three patients' lesions showed variable (18)F-FDG avidity, uptake on (68)Ga-DOTATATE PET was comparatively intense. The small case series illustrates the need to consider ccRCC in the differential diagnosis of (68)Ga-DOTATATE avid lesions.
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spelling pubmed-60345482018-07-20 Metastatic clear cell renal cell carcinoma demonstrating intense uptake on (68)Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature Nadebaum, David P. Lee, Sze Ting Nikfarjam, Mehrdad Scott, Andrew M. World J Nucl Med Case Report (68)Ga-DOTATATE positron emission tomography (PET) is a molecular imaging technology which has shown superiority over (111)In-octreotide scanning for the detection and staging of neuroendocrine tumors. We report three patients with pancreatic masses that were ultimately diagnosed as clear cell renal cell carcinoma (ccRCC) metastases on histopathology. During their initial diagnostic assessment, the three patients underwent both (18)F-fluorodeoxyglucose ((18)F-FDG) and (68)Ga-DOTATATE PET. While all three patients' lesions showed variable (18)F-FDG avidity, uptake on (68)Ga-DOTATATE PET was comparatively intense. The small case series illustrates the need to consider ccRCC in the differential diagnosis of (68)Ga-DOTATATE avid lesions. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6034548/ /pubmed/30034285 http://dx.doi.org/10.4103/wjnm.WJNM_38_17 Text en Copyright: © 2018 World Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Nadebaum, David P.
Lee, Sze Ting
Nikfarjam, Mehrdad
Scott, Andrew M.
Metastatic clear cell renal cell carcinoma demonstrating intense uptake on (68)Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature
title Metastatic clear cell renal cell carcinoma demonstrating intense uptake on (68)Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature
title_full Metastatic clear cell renal cell carcinoma demonstrating intense uptake on (68)Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature
title_fullStr Metastatic clear cell renal cell carcinoma demonstrating intense uptake on (68)Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature
title_full_unstemmed Metastatic clear cell renal cell carcinoma demonstrating intense uptake on (68)Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature
title_short Metastatic clear cell renal cell carcinoma demonstrating intense uptake on (68)Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature
title_sort metastatic clear cell renal cell carcinoma demonstrating intense uptake on (68)ga-dotatate positron emission tomography: three case reports and a review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034548/
https://www.ncbi.nlm.nih.gov/pubmed/30034285
http://dx.doi.org/10.4103/wjnm.WJNM_38_17
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