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Older adults in phase I clinical trials: a comparative analysis of participation and clinical benefit rate among older adults versus middle age and AYA patients on phase I clinical trials with VEGF/VEGFR inhibitors
BACKGROUND: Older adults aged 65 years and above remain underrepresented in cancer clinical trials. We hypothesized that older participation in early phase trials with VEGF/VEGFR (VEGF/R) inhibitors was lower than cancer prevalence in this group and lower than other age groups (middle age, adolescen...
Autores principales: | Subbiah, Ishwaria M., Tang, Chad, Rao, Arvind, Falchook, Gerald S., Subbiah, Vivek, Tsimberidou, Apostolia M., Karp, Daniel, Kurzrock, Razelle, Hong, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034739/ https://www.ncbi.nlm.nih.gov/pubmed/29989021 http://dx.doi.org/10.18632/oncotarget.25571 |
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