Involvement of anti-tumor miR-124-3p and its targets in the pathogenesis of pancreatic ductal adenocarcinoma: direct regulation of ITGA3 and ITGB1 by miR-124-3p

MicroRNAs (miRNAs) are unique in that a single miRNA molecule regulates a vast number of RNA transcripts. Thus, aberrantly expressed miRNAs disrupt tightly controlled RNA networks in cancer cells. Our functional screening showed that expression of miR-124-3p was downregulated in pancreatic ductal ad...

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Detalles Bibliográficos
Autores principales: Idichi, Tetsuya, Seki, Naohiko, Kurahara, Hiroshi, Fukuhisa, Haruhi, Toda, Hiroko, Shimonosono, Masataka, Yamada, Yasutaka, Arai, Takayuki, Kita, Yoshiaki, Kijima, Yuko, Mataki, Yuko, Maemura, Kosei, Natsugoe, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034741/
https://www.ncbi.nlm.nih.gov/pubmed/29988949
http://dx.doi.org/10.18632/oncotarget.25599

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