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Real world experience in low-dose ipilimumab in combination with PD-1 blockade in advanced melanoma patients
Dual immune-checkpoint blockade with the anti-PD-1 antibody nivolumab (1 mg/kg) and standard-dose ipilimumab (3 mg/kg) is the mainstay of immunotherapy in advanced melanoma and it is approved since 2016. However, severe side effects (grade 3/4) occur in up to 60% of the patients. Recently, clinical...
Autores principales: | Kirchberger, Michael Constantin, Moreira, Alvaro, Erdmann, Michael, Schuler, Gerold, Heinzerling, Lucie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034742/ https://www.ncbi.nlm.nih.gov/pubmed/29988983 http://dx.doi.org/10.18632/oncotarget.25627 |
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