Cargando…

Harnessing RIG-I and intrinsic immunity in the tumor microenvironment for therapeutic cancer treatment

Cancer immunotherapies that remove checkpoint restraints on adaptive immunity are gaining clinical momentum. Approaches aimed at intrinsic cellular immunity in the tumor microenvironment are less understood, but are of intense interest, based on their ability to induce tumor cell apoptosis while orc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elion, David L., Cook, Rebecca S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034747/ https://www.ncbi.nlm.nih.gov/pubmed/29989043 http://dx.doi.org/10.18632/oncotarget.25626

Ejemplares similares

Activation of RIG-I signaling to increase the pro-inflammatory phenotype of a tumor
por: Elion, David L., et al.
Publicado: (2019)

Therapeutics to harness the immune microenvironment in multiple myeloma
por: Ignatz-Hoover, James J., et al.
Publicado: (2022)

Harnessing the Activation of RIG-I Like Receptors to Inhibit Glioblastoma Tumorigenesis
por: Bufalieri, Francesca, et al.
Publicado: (2021)

Hepatitis B virus inhibits intrinsic RIG-I and RIG-G immune signaling via inducing miR146a
por: Hou, Zhaohua, et al.
Publicado: (2016)

RIG-I Like Receptors in Antiviral Immunity and Therapeutic Applications
por: Ireton, Reneé C., et al.
Publicado: (2011)

Tumor suppressor activity of RIG-I
por: Li, Xian-Yang, et al.
Publicado: (2014)

Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling
por: Guo, Guijie, et al.
Publicado: (2021)

RIG-I like receptor sensing of host RNAs facilitates the cell-intrinsic immune response to KSHV infection
por: Zhao, Yang, et al.
Publicado: (2018)

Normalization of the tumor microenvironment by harnessing vascular and immune modulation to achieve enhanced cancer therapy
por: Choi, Yechan, et al.
Publicado: (2023)

RIG‐I‐mediated innate immune signaling in tumors reduces the therapeutic effect of oncolytic vesicular stomatitis virus
por: Zhang, Pengfei, et al.
Publicado: (2022)

Harnessing nanomedicine to overcome the immunosuppressive tumor microenvironment
por: Sun, Bo, et al.
Publicado: (2020)

Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling
por: Nguyen, Kim Bich, et al.
Publicado: (2019)

Host and Viral Modulation of RIG-I-Mediated Antiviral Immunity
por: Liu, Yiliu, et al.
Publicado: (2017)

Mutant RIG-I enhances cancer-related inflammation through activation of circRIG-I signaling
por: Song, Jia, et al.
Publicado: (2022)

The intrinsically disordered CARDs‐Helicase linker in RIG‐I is a molecular gate for RNA proofreading
por: Schweibenz, Brandon D, et al.
Publicado: (2022)

Establishing the role of ATP for the function of the RIG-I innate immune sensor
por: Rawling, David C, et al.
Publicado: (2015)

RIG-I-like receptor regulation in virus infection and immunity
por: Chan, Ying Kai, et al.
Publicado: (2015)

Targeting intrinsic RIG-I signaling turns melanoma cells into type I interferon-releasing cellular antitumor vaccines
por: Bek, Sarah, et al.
Publicado: (2019)

Intrinsic RIG-I restrains STAT5 activation to modulate antitumor activity of CD8(+) T cells
por: Jiang, Xinyi, et al.
Publicado: (2023)

Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5
por: Brisse, Morgan, et al.
Publicado: (2019)

The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization
por: Wang, Wenshuai, et al.
Publicado: (2023)

Harnessing Biomaterials to Engineer the Lymph Node Microenvironment for Immunity or Tolerance
por: Andorko, James I., et al.
Publicado: (2014)

Harnessing the innate immune system and local immunological microenvironment to treat colorectal cancer
por: Kather, Jakob Nikolas, et al.
Publicado: (2019)

Harnessing the soil: reshaping the tumor microenvironment towards an antitumor immune state by low‐dose metformin
por: Lin, Yusheng, et al.
Publicado: (2021)

Translational Horizons in the Tumor Microenvironment: Harnessing Breakthroughs and Targeting Cures
por: Sun, Yu
Publicado: (2015)

Systems-based Analysis of RIG-I-dependent Signaling Identifies KHSRP as an Inhibitor of RIG-I Receptor Activation
por: Soonthornvacharin, Stephen, et al.
Publicado: (2017)

The Innate Immune Signalling Pathways: Turning RIG-I Sensor Activation against Cancer
por: Iurescia, Sandra, et al.
Publicado: (2020)

RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity
por: Ramos, Hilario J, et al.
Publicado: (2011)

RIG-I contributes to the innate immune response after cerebral ischemia
por: Brand, Frank J., et al.
Publicado: (2015)

RIG-I in RNA virus recognition
por: Kell, Alison M., et al.
Publicado: (2015)

Therapeutic Targeting of RIG-I and MDA5 Might Not Lead to the Same Rome
por: Kasumba, Dacquin M., et al.
Publicado: (2019)

Harnessing the Immune System with Cancer Vaccines: From Prevention to Therapeutics
por: Le, Ilene, et al.
Publicado: (2022)

Frenemies in the Microenvironment: Harnessing Mast Cells for Cancer Immunotherapy
por: Sulsenti, Roberta, et al.
Publicado: (2023)

Harnessing the cDC1-NK Cross-Talk in the Tumor Microenvironment to Battle Cancer
por: Bödder, Johanna, et al.
Publicado: (2021)

Harnessing the immune response to target tumors
por: Manning, Luisa, et al.
Publicado: (2017)

Harnessing type I interferon-mediated immunity to target malignant brain tumors
por: Lim, Juhee, et al.
Publicado: (2023)

RIG-I promotes immune evasion of colon cancer by modulating PD-L1 ubiquitination
por: Zhang, Yangyang, et al.
Publicado: (2023)

Antiviral Activity of Canine RIG-I against Canine Influenza Virus and Interactions between Canine RIG-I and CIV
por: Wang, Zhen, et al.
Publicado: (2021)

Analysis of Porcine RIG-I Like Receptors Revealed the Positive Regulation of RIG-I and MDA5 by LGP2
por: Li, Shuangjie, et al.
Publicado: (2021)

Nuclear-resident RIG-I senses viral replication inducing antiviral immunity
por: Liu, GuanQun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_44oujn0prtomblni1ea9s80m2d