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The emergence of trophoblast cell-surface antigen 2 (TROP-2) as a novel cancer target
TROP-2 is a glycoprotein first described as a surface marker of trophoblast cells, but subsequently shown to be increased in many solid cancers, with lower expression in certain normal tissues. It regulates cancer growth, invasion and spread by several signaling pathways, and has a role in stem cell...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034748/ https://www.ncbi.nlm.nih.gov/pubmed/29989029 http://dx.doi.org/10.18632/oncotarget.25615 |