New generation sequencing of targeted genes in the classical and the variant form of hairy cell leukemia highlights mutations in epigenetic regulation genes

Classical hairy cell leukemia (HCL-c) is a rare lymphoid neoplasm. BRAF(V600E) mutation, detected in more than 80% of the cases, is described as a driver mutation, but additional genetic abnormalities appear to be necessary for the disease progression. For cases of HCL-c harboring a wild-type BRAF g...

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Detalles Bibliográficos
Autores principales: Maitre, Elsa, Bertrand, Philippe, Maingonnat, Catherine, Viailly, Pierre-Julien, Wiber, Margaux, Naguib, Dina, Salaün, Véronique, Cornet, Edouard, Damaj, Gandhi, Sola, Brigitte, Jardin, Fabrice, Troussard, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034755/
https://www.ncbi.nlm.nih.gov/pubmed/29989027
http://dx.doi.org/10.18632/oncotarget.25601

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