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Design of a novel filter paper based construct for rapid analysis of acetone
The present work was focused to design a cheap, rapid, portable and easy to use filter paper based assay for the qualitative and quantitate analysis of acetone. Sodium alginate gel was loaded with the acetone specific optical signal probe, and subsequently coated onto filter paper surface to design...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034825/ https://www.ncbi.nlm.nih.gov/pubmed/29979737 http://dx.doi.org/10.1371/journal.pone.0199978 |
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author | Rauf, Sajid Ali, Yaqeen Hussain, Sabir Ullah, Fakhar Hayat, Akhtar |
author_facet | Rauf, Sajid Ali, Yaqeen Hussain, Sabir Ullah, Fakhar Hayat, Akhtar |
author_sort | Rauf, Sajid |
collection | PubMed |
description | The present work was focused to design a cheap, rapid, portable and easy to use filter paper based assay for the qualitative and quantitate analysis of acetone. Sodium alginate gel was loaded with the acetone specific optical signal probe, and subsequently coated onto filter paper surface to design portable colorimetric assays for acetone monitoring. The color of the paper sensor strip was observed to change from dark yellow to light yellowish in the presence of varying concentrations of acetone. Three different color analyzing models including RGB, HSV, and LAB were employed to probe the output optical signal, and their performance was compared in terms of better interpretation of the generated signal. The LAB model was found to provide better analytical figures of merit with a linear response for the acetone concentration ranging from 2.5 to 1500 ppm, and a limit of detection of 0.5 ppm. Furthermore, the specificity of the designed filter paper based sensor was demonstrated against different common interfering compounds. The results demonstrated the potential of our proposed filter paper based sensor as a novel tool for the analysis of acetone. |
format | Online Article Text |
id | pubmed-6034825 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-60348252018-07-19 Design of a novel filter paper based construct for rapid analysis of acetone Rauf, Sajid Ali, Yaqeen Hussain, Sabir Ullah, Fakhar Hayat, Akhtar PLoS One Research Article The present work was focused to design a cheap, rapid, portable and easy to use filter paper based assay for the qualitative and quantitate analysis of acetone. Sodium alginate gel was loaded with the acetone specific optical signal probe, and subsequently coated onto filter paper surface to design portable colorimetric assays for acetone monitoring. The color of the paper sensor strip was observed to change from dark yellow to light yellowish in the presence of varying concentrations of acetone. Three different color analyzing models including RGB, HSV, and LAB were employed to probe the output optical signal, and their performance was compared in terms of better interpretation of the generated signal. The LAB model was found to provide better analytical figures of merit with a linear response for the acetone concentration ranging from 2.5 to 1500 ppm, and a limit of detection of 0.5 ppm. Furthermore, the specificity of the designed filter paper based sensor was demonstrated against different common interfering compounds. The results demonstrated the potential of our proposed filter paper based sensor as a novel tool for the analysis of acetone. Public Library of Science 2018-07-06 /pmc/articles/PMC6034825/ /pubmed/29979737 http://dx.doi.org/10.1371/journal.pone.0199978 Text en © 2018 Rauf et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Rauf, Sajid Ali, Yaqeen Hussain, Sabir Ullah, Fakhar Hayat, Akhtar Design of a novel filter paper based construct for rapid analysis of acetone |
title | Design of a novel filter paper based construct for rapid analysis of acetone |
title_full | Design of a novel filter paper based construct for rapid analysis of acetone |
title_fullStr | Design of a novel filter paper based construct for rapid analysis of acetone |
title_full_unstemmed | Design of a novel filter paper based construct for rapid analysis of acetone |
title_short | Design of a novel filter paper based construct for rapid analysis of acetone |
title_sort | design of a novel filter paper based construct for rapid analysis of acetone |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034825/ https://www.ncbi.nlm.nih.gov/pubmed/29979737 http://dx.doi.org/10.1371/journal.pone.0199978 |
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